The Nephrology Division at the MUHC provides patient care and teaching and conducts research, in various aspects of the pathophysiology and treatment of kidney disease.

NephroCAGE Consortium Partner and an associate professor at department of Medicine, McGill University and and Co-Lead of Genome Canada Transplant Consortium and Co-Director of the MUHC Kidney Disease Biorepository

Dr. Sapir-Pichhadze

Dr. Ruth Sapir-Pichhadze is an Associate Professor, Division of Nephrology, Faculty of Medicine, McGill University and a Clinician Scientist, Research Institute of the McGill University Health Centre. She obtained her Bachelor of Science and MD from the Hebrew University, Jerusalem, Israel. She completed her medical specialization in Internal Medicine, Nephrology, and Kidney Transplantation at the University of Toronto. She is a graduate of the Eliot Phillipson Clinician Scientist Training Program and received her Master of Science and a PhD in Clinical Epidemiology in the Institute of Health Policy, Management and Evaluation at the University of Toronto. 

Dr. Sapir-Pichhadze is the Co-Lead of the Genome Canada Transplant Consortium and the Co-Director of the MUHC Kidney Disease Biorepository – from Birth to Adulthood. Dr. Sapir-Pichhadze serves on the Steering Committees of AST-REG-WIT and NephroCAGE, Canadian-German Consortium on Artificial Intelligence for Improved Kidney Transplantation Outcomes. She served on the task force charged with developing Canadian Clinical Practice Guidelines for Solid Organ Donation and Transplantation during the COVID-19 pandemic and the Central Review Committee of the 2020 Canadian Hypertension guidelines. She is a member of WIT Pillars II and III and the Immune-Mediated Injury Working Group of the Banff Foundation. She also serves as the Chair of the Training & Mentorship Committee of the Canadians Seeking Solutions and Innovations to Overcome Chronic Kidney Disease (Can-SOLVE CKD) Network, which oversees the development of resources and tools for capacity building in Patient-Oriented Research. 

Dr. Sapir-Pichhadze’s program is funded by Genome Canada, the Canadian Institutes of Health Research, and Fonds de Recherche du Québec. Her research focuses on the application of Precision Medicine strategies for the prevention of immune-mediated injuries. Specifically, she is interested in identifying genetic determinants of donor and recipient compatibility to optimize organ allocation schemes, inform personalized surveillance schedules, and establish individually tailored therapeutic regimens in kidney transplant candidates and recipients. The overarching goals of Dr. Sapir-Pichhadze’s research program is to optimize the quantity and quality of life of patients with kidney disease. 

Dr. Sapir-Pichhadze’s research focuses on studying the determinants of kidney transplant outcomes. She is particularly interested in identifying strategies to prevent immune-mediated injuries following kidney transplantation. Methodologically, She has experience in observational studies using large registries and single centre databases, health services research, systematic reviews, decision analyses, epidemiologic methods for evaluating diagnostic test accuracy in the presence or absence of a gold standard, as well as analytic methods capable of dealing with time-varying variables and competing risks.