The Karlsruhe Institute of Technology (KIT) with the research group Critical Information Infrastructures (CII) at the Institute of Applied Informatics and Formal Description Methods (AIFB) headed by Prof. Dr. Ali Sunyaev, deals with research questions related to the design, development, and evaluation of trustworthy, privacy-preserving, and user-friendly information system. In this context, critical information infrastructures, especially in health care, are a central research topic of Ali Sunyaev.

With regard to the privacy-preserving and user-friendly design of health information systems, KIT has created a data privacy-promoting architecture for the processing of genome data in cloud computing environments in the BMBF funded project Multi-Disciplinary Identification of Lineage-Specific Signaling Dependencies in Cancer (MILES). In two research projects funded by the Helmholtz Association, KIT investigates the application of distributed ledger technology (e.g., Blockchain) to the management of genomic research data (project: DLT4Life) and explainable artificial intelligence approaches for life science machine learning problems (XAIomics).

In the BMWi-funded research project Blockchain-based Health Data Management for Holistic Health Profiles (BloG3), KIT is responsible for the design of the Blockchain layer of the platform as well as the user-centered evaluation of the platform. In the industry-funded project Trusted Blockchain, KIT has researched quality criteria for blockchain-based systems. Within the BMWi-funded project European Cloud Service Data Protection Certification (AUDITOR), KIT also deals with the design and certification of information systems in accordance with the EU Data Protection Basic Regulation (EU-GDPR).